SAMe (400 mg) Enteric Coated Tablets
Suitable for vegetarians
- Science-based nutrition
- Dietary supplement
- Enhances mood and neural function*
- Promotes joint comfort and mobility*
- Supports liver health and detoxification*
Our Double-Strength SAMe 400 contains 400 mg of
active SAMe in each tablet. Doctor's Best utilizes only the highest
quality Italian SAMe available on the market. This ensures that you
receive the most potent SAMe product with the highest percentage of the
active S,S form per serving, bar none.
S-Adenosyl Methionine (SAMe) is derived from the amino acid
methionine and is one of the most important methyl donors in the central
nervous system. Methylation (donation of methyl groups) is an essential
process in ensuring the proper function of a number of organ systems.
SAMe is involved in numerous biochemical reactions in tissue including
the liver, joints and brain. SAMe is also required for the biosynthesis
of critical neurotransmitters and hormones.
Supplementing with SAMe
The manufacturing process
of SAMe yields two forms, the S,S and the R,S isomers. The S,S isomer
is the active form that mediates biochemical activity in the human body,
whereas the R,S form is considered to be biologically inactive. The
Italian SAMe used in Double-Strength SAMe 400 is processed to yield the
highest available percentage of the active pure S,S form on the market.
SAMe and Joint Function
SAMe may enhance
cartilage protection and promote the synthesis of proteoglycans,
essential components of connective tissue. Clinical studies show an
ability of SAMe to enhance mobility and movement, and promote joint
comfort.*
SAMe and Neural Health
SAMe-catalyzed methylation
reactions promote the synthesis of neurotransmitters, which have the
potential to promote enhanced mood. SAMe may also upregulate the
production of phosphatidylcholine, supporting cognitive function.*
SAMe and Liver Function
SAMe enhances liver
synthesis of glutathione, an antioxidant. Glutathione promotes
detoxification and liver protection. Studies show SAMe may protect liver
tissue from injury caused by a number of toxins.*
Individuals using antidepressant medications should consult with
their prescribing physician prior to using this product. Individuals
diagnosed with bipolar disease or manic depression should avoid
supplementing with SAMe. Do not use if pregnant or nursing. May cause
gastrointestinal discomfort in a small percentage of people.
Suggested Adult Use: Take 1 tablet daily away from food, or as directed by a health care professional. Do not chew or crush tablet.
Supplement Facts
Serving Size: 1 Tablet
Serving per container: 30 servings
Amount Per Serving %DV
S-Adenosyl Methionine 400 mg †
(from 800 mg of SAM-e tosylate disulfate)
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Other Ingredients: Cellulose gel, methacrylic acid
copolymer, compritol 888ATO, talc, triethyl citrate, titanium dioxide,
magnesium stearate, mannitol, glycerol palmitostearate, silica, medium
chain triglycerides, sodium starch glycolate, and iron oxide.
Store in a cool, dry place to ensure maximum quality.
Contains nothing other than listed ingredients.
400mg, 30 Enteric Coated Tabs